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DeCS
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Descriptor English:
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Oncogene Protein gp140(v-fms)
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Descriptor Spanish:
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Proteína Oncogénica gp140(v-fms)
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Descriptor Portuguese:
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Proteína Oncogênica gp140(v-fms)
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Synonyms English:
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fms Oncogene Protein gp120
fms Oncogene Protein gp140
gp120(v-fms)
gp140(v-fms)
v-fms Protein
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Tree Number:
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D12.776.624.664.520.750.650
D12.776.964.700.750.650
D12.776.964.775.750.650
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Definition English:
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Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms). |
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Indexing Annotation English:
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IM; coord with specific virus (IM); /drug eff /ultrastruct permitted; DF: note short X refs
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History Note English:
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91
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Allowable Qualifiers English:
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Record Number:
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29067
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Unique Identifier:
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D016281
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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